Mothers-to-be should weigh risks of antidepressants during pregnancy
April 23rd, 2009 by Jennifer Walker-Journey
Years ago, it was thought that pregnancy protected women from depression, but researchers have since learned that being pregnant and recent childbirth may actually contribute to a woman’s depression, filling her with a range of emotions that make dealing with the symptoms of the condition even more difficult. According to the Mayo Clinic, an estimated 10 percent of women experience depression during pregnancy.
Seeking help from a health care provider is vital not only to the mother, but to her unborn child. Depressed mothers-to-be may not have the energy to take care of themselves or seek optimal prenatal care. She may even rely on smoking cigarettes or drinking alcohol to cope, which can have detrimental effects on an unborn child. Health care providers can discuss healthier options, such as group or one-on-one therapy. In some cases, antidepressants may be recommended.
According to the Mayo Clinic, few medications have been proven safe beyond a doubt for use during pregnancy, which is why many doctors advise their patients who are pregnant or are considering pregnancy to wean off most drugs. However, some antidepressants, such as selective serotonin reuptake inhibitors (SSRIs), should only be taken during pregnancy after a woman weighs the risks with her doctor because of the possibility of serious birth defects.
Common SSRIs that have previously been prescribed for depression during pregnancy include Celexa, Prozac, Zoloft and Paxil. However, with all those medications there is a possible risk of persistent pulmonary hypertension, or PPHN, in the newborn. The risk is so rare that Celexa, Prozac and Zoloft are still considered options for use during pregnancy.
However, in 2005, a scientific study indicated that women who took Paxil during the first three months of pregnancy had a greater risk of their unborn child developing birth defects – in particular heart defects – than any other antidepressant. As a result of that study, GlaxoSmithKline, makers of Paxil, updated the PRECAUTIONS section of its medication label discouraging use of Paxil during pregnancy.
The Mayo Clinic urges women to consult with their doctors and learn the risks and benefits of antidepressants during pregnancy before making a decision.
Related posts:
- Study: antidepressants, depression linked to preterm birth
- Child is helpless victim of mother’s use of Paxil during pregnancy
- Treatment Challenges of Depression in Pregnancy and the Possibility of Persistent Pulmonary Hypertension in Newborns
- ACOG Issues Opinion on SSRI Antidepressant Use During Pregnancy
- Updated Product Labeling Warns of Birth Defect
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